PPAR α (Phospho Ser21) rabbit pAb

Ref. EK-ES20158

Informations sur le produit

• Nom: PPAR α (Phospho Ser21) rabbit pAb
• Synonymes: Peroxisome proliferator-activated receptor alpha (PPAR-alpha;Nuclear receptor subfamily 1 group C member 1)

Description

function:Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.,online information:Peroxisome proliferator-activated receptor entry,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Heterodimer with the retinoid X receptor. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Also interacts with PPARBP coactivator in vitro. Interacts with AKAP13.,tissue specificity:Skeletal muscle, liver, heart and kidney.,

• Marque: ELK Biotechnology