SIRT1 (phospho-Ser549) rabbit pAb

Ref. EK-ES20206

Informations sur le produit

• Nom: SIRT1 (phospho-Ser549) rabbit pAb
• Synonymes: NAD-dependent protein deacetylase sirtuin-1 (hSIRT1;EC 3.5.1.-;Regulatory protein SIR2 homolog 1;SIR2-like protein 1;hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]

Description

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008],

• Marque: ELK Biotechnology