FAST rabbit pAb

Ref. EK-ES2328

Informations sur le produit

• Nom: FAST rabbit pAb
• Synonymes: FASTK; Fas-activated serine/threonine kinase; FAST kinase

Description

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008],

• Marque: ELK Biotechnology