Frizzled-7 rabbit pAb

Ref. EK-ES2373

Informations sur le produit

• Nom: Frizzled-7 rabbit pAb
• Synonymes: FZD7; Frizzled-7; Fz-7; hFz7; FzE3

Description

frizzled class receptor 7(FZD7) Homo sapiens Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008],

• Marque: ELK Biotechnology