MyD88 rabbit pAb

Ref. EK-ES2871

Informations sur le produit

• Nom: MyD88 rabbit pAb
• Synonymes: MYD88; Myeloid differentiation primary response protein MyD88

Description

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],

• Marque: ELK Biotechnology