UBE3C rabbit pAb

Ref. EK-ES3667

Informations sur le produit

• Nom: UBE3C rabbit pAb
• Synonymes: UBE3C; KIAA0010; KIAA10; Ubiquitin-protein ligase E3C; HectH2

Description

function:E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.,miscellaneous:A cysteine residue is required for ubiquitin-thioester formation.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 1 IQ domain.,subunit:Interacts with 26S proteasomes. Binds CAND2.,tissue specificity:Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas.,

• Marque: ELK Biotechnology