GDF-3 rabbit pAb

Ref. EK-ES4373

Informations sur le produit

• Nom: GDF-3 rabbit pAb
• Synonymes: GDF3; Growth/differentiation factor 3; GDF-3

Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],

• Marque: ELK Biotechnology