GDF-6 rabbit pAb

Ref. EK-ES4378

Informations sur le produit

• Nom: GDF-6 rabbit pAb
• Synonymes: GDF6; GDF16; Growth/differentiation factor 6; GDF-6; Growth/differentiation factor 16

Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016],

• Marque: ELK Biotechnology