GDF-7 rabbit pAb

Ref. EK-ES4379

Informations sur le produit

• Nom: GDF-7 rabbit pAb
• Synonymes: GDF7; Growth/differentiation factor 7; GDF-7

Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016],

• Marque: ELK Biotechnology