LDOC1 rabbit pAb

Ref. EK-ES5375

Informations sur le produit

• Nom: LDOC1 rabbit pAb
• Synonymes: LDOC1; BCUR1; Protein LDOC1; Leucine zipper protein down-regulated in cancer cells

Description

The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008],

• Marque: ELK Biotechnology