β-1,4-GalNAc-T rabbit pAb

Ref. EK-ES6769

Informations sur le produit

• Nom: β-1,4-GalNAc-T rabbit pAb
• Synonymes: CSGALNACT1; CHGN; GALNACT1; Chondroitin sulfate N-acetylgalactosaminyltransferase 1; CsGalNAcT-1; Chondroitin beta-1; 4-N-acetylgalactosaminyltransferase 1; Beta4GalNAcT-1

Description

catalytic activity:UDP-N-acetyl-D-galactosamine + beta-D-glucuronyl-(1->3)-D-galactosyl-proteoglycan = UDP + N-acetyl-D-galactosaminyl-(1->4)-beta-D-glucuronyl-(1->3)-beta-D-galactosylproteoglycan.,function:Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage.,online information:Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1,online information:GlycoGene database,PTM:N-glycosylated.,similarity:Belongs to the chondroitin N-acetylgalactosaminyltransferase family.,tissue specificity:Ubiquitous, with the highest levels in placenta, thyroid, bladder, prostate and adrenal gland. Detected at low levels in the other tissues examined.,

• Marque: ELK Biotechnology