BID (phospho Ser78) rabbit pAb

Ref. EK-ES7131

Informations sur le produit

• Nom: BID (phospho Ser78) rabbit pAb
• Synonymes: BID; BH3-interacting domain death agonist; p22 BID; BID

Description

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008],

• Marque: ELK Biotechnology