N-CoR rabbit pAb

Ref. EK-ES8074

Informations sur le produit

• Nom: N-CoR rabbit pAb
• Synonymes: NCOR1; KIAA1047; Nuclear receptor corepressor 1; N-CoR; N-CoR1

Description

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010],

• Marque: ELK Biotechnology