BMP-9 rabbit pAb

Ref. EK-ES8713

Informations sur le produit

• Nom: BMP-9 rabbit pAb
• Synonymes: Growth/differentiation factor 2 (GDF-2;Bone morphogenetic protein 9;BMP-9)

Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jul 2016],

• Marque: ELK Biotechnology