PCNA rabbit pAb

Ref. EK-ES8839

Informations sur le produit

• Nom: PCNA rabbit pAb
• Synonymes: Proliferating cell nuclear antigen (PCNA) (Cyclin)

Description

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],

• Marque: ELK Biotechnology