Roflumilast

CAS : 162401-32-3

Ref. TM-T1024

Informations sur le produit

• Nom: Roflumilast
• Synonymes: B9302-107, BYK 20869, APTA 2217, BY 217, 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide, 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide, Arq 151, B 9302-107, Benzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-, By 217, Byk 20869, Daliresp, Daxas, Libertek, N-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
• CAS: 162401-32-3

Description

Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its active metabolite roflumilast N-oxide selectively and competitively bind to and inhibit PDE4, which leads to an increase of both intracellular levels of cyclic-3', 5'-adenosine monophosphate (cAMP) and cAMP-mediated signaling.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 403.21
• Formule: C₁₇H₁₄Cl₂F₂N₂O₃
• Degré de pureté: 100.00%
• Couleur/Forme: Solid