Dihydroergocristine mesylate
CAS : 24730-10-7
Ref. TM-T11043
1mg | 57,00 € | ||
5mg | 123,00 € | ||
10mg | 188,00 € | ||
25mg | 314,00 € | ||
50mg | 468,00 € | ||
100mg | 628,00 € | ||
1ml*10 (DMSO) | 184,00 € |
Informations sur le produit
- DHEC (mesylate)
- (5'Alpha,10Alpha)-5'-Benzyl-12'-Hydroxy-3',6',18-Trioxo-2'-(Propan-2-Yl)-9,10-Dihydroergotaman Methanesulfonate (1:1)
- 5'alpha-Benzyl-9,10alpha-dihydro-12'-hydroxy-2'-isopropylergotaman-3',6',18-trione monomethanesulphonate
- 9,10-Dihydroergocristine methanesulfonate
- Dihydroergocristine methanesulfonate
- Dihydroergocristinmesilat
- Dihydroergocristinmesilat [German]
- Ergocristine, 9,10-dihydro-, monomethanesulfonate (salt)
- Ergocristine, dihydro-, methanesulfonate
- Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)-, (5'alpha,10alpha)-, monomethanesulfonate (salt)
- Voir d'autres synonymes
- Ergotaman-3′,6′,18-trione, 9,10-dihydro-12′-hydroxy-2′-(1-methylethyl)-5′-(phenylmethyl)-, (5′α,10α)-, methanesulfonate (1:1)
- Ergotaman-3′,6′,18-trione, 9,10-dihydro-12′-hydroxy-2′-(1-methylethyl)-5′-(phenylmethyl)-, (5′α,10α)-, monomethanesulfonate (salt)
- Ergotamane-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)-, (5'-alpha,10-alpha)-, monomethanesulfonate (salt)
- GNF Pf 3462
- Unii-Ds7Cl18Uam
Dihydroergocristine mesylate (DHEC (mesylate))(DHEC mesylate) is the methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomatic treatment of mental deterioration associated with cerebrovascular insufficiency and in peripheral vascular disease. Dihydroergocristine mesylate is a inhibitor of γ-secretase (GSI), , reduces the production of the Alzheimer's disease amyloid-β peptides, binds directly to γ-secretase and Nicastrin with equilibrium dissociation constants (Kd) of 25.7 nM and 9.8 μM, respectively[1]. It is also a component of ergoloid mesylate (codergocrine mesilate), a mixture of ergot alkaloid derivatives that is used as a vasodilator and has shown mild benefits in the treatment of vascular dementia. It has a role as a vasodilator agent, an alpha-adrenergic antagonist and a geroprotector. It contains a dihydroergocristine.
Propriétés chimiques
Question d’ordre technique sur : TM-T11043 Dihydroergocristine mesylate
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