Bestatin

CAS : 58970-76-6

Ref. TM-T1257

Informations sur le produit

• Nom: Bestatin
• Synonymes: Ubenimex, <span class="text-smallcaps">L</span>-Leucine, N-(3-amino-2-hydroxy-1-oxo-4-phenylbutyl)-, [S-(R*,S*)]-, <span class="text-smallcaps">L</span>-Leucine, N-[(2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbutyl]-, Bestain, N-(3-amino-2-hydroxy-4-phenylbutanoyl)leucine, N-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbutyl]-<span class="text-smallcaps">L</span>-leucine, N-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]-D-leucine, N-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]-L-leucine, N-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]leucine, NSC 265489, Nk 421
• CAS: 58970-76-6

Description

Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Aminopeptidases has been implicated in the process of cell adhesion and invasion of tumor cells. Therefore, inhibiting aminopeptidases may partially attribute to the antitumor effect of ubenimex. This agent also activates T lymphocyte, macrophage, and bone marrow stem cell as well as stimulates the release of interleukin-1 and -2, thus further enhances its antitumor activity.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 308.37
• Formule: C₁₆H₂₄N₂O₄
• Degré de pureté: 100%
• Couleur/Forme: White Crystalline Powder