PXS-5153A monohydrochloride

CAS : 2125956-82-1

Ref. TM-T12585L

Informations sur le produit

• Nom: PXS-5153A monohydrochloride
• Synonymes: PXS-5153A monohydrochloride (2125956-82-1 free base)
• CAS: 2125956-82-1

Description

PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC 50 of <40 nM for LOXL2 across all mammalian species and an IC 50 of 63 nM for human LOXL3. PXS-5153A monohydrochloride dose-dependently reduced LOXL2-mediated collagen oxidation and collagen crosslinking in vitro which may represent an innovative therapeutic approach for the treatment of fibrosis

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 475.41
• Formule: C₂₀H₂₅Cl₂FN₄O₂S
• Degré de pureté: 98%
• Couleur/Forme: Solid