Capecitabine

CAS : 154361-50-9

Ref. TM-T1408

Informations sur le produit

• Nom: Capecitabine
• Synonymes: Xeloda, Capecitibine, Capiibine, RO 09-1978, 1-(5-deoxypentofuranosyl)-5-fluoro-4-{[(pentyloxy)carbonyl]amino}pyrimidin-2(1H)-one, 5-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine, 5′-Deoxy-5-fluoro-N⁴-(pentyloxycarbonyl)cytidine, Capacetrine, Capecitabine Accord, Capecitabine Medac, Capecitabine SUN, Capecitabine Teva, Capecitibine, Capecytabine, Capiibine, Captabin, Carbamic acid, [1-(5-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl]-, pentyl ester, Cytidine, 5′-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]-, Ecansya, N4-[(pentyloxy)carbonyl]-5'-deoxy-5-fluorocytidine, N⁴-Pentyloxycarbonyl-5′-deoxy-5-fluorocytidine, Pentyl [1-(3,4-dihydroxy-5-methyl-oxolan-2-yl)-5-fluoro-2-oxo-pyrimidin-4-yl]aminoformate, R-340, Ro 09-1978/000, Ro-09-1978, Xeloda, Xeltabin
• CAS: 154361-50-9

Description

Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 359.35
• Formule: C₁₅H₂₂FN₃O₆
• Degré de pureté: 100%
• Couleur/Forme: Less Solid Colourless Solid