BMS-906024

CAS : 1401066-79-2

Ref. TM-T14680

Informations sur le produit

• Nom: BMS-906024
• Synonymes: Osugacestat, AL-101, BM-0018
• CAS: 1401066-79-2

Description

BMS-906024 (Osugacestat) is an orally available and selective inhibitor of γ-secretase, a small molecule Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity against a variety of human cancer xenografts.BMS-906024 prevents the activation of all four Notch receptors, and is active against Notch1, -2, -3 and -4 receptors. BMS-906024 prevents the activation of all four Notch receptors, with IC50s of 1.6, 0.7, 3.4 and 2.9 nM for Notch1, -2, -3 and -4 receptors, respectively.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 556.5
• Formule: C₂₆H₂₆F₆N₄O₃
• Degré de pureté: 100%
• Couleur/Forme: Solid