DSS Crosslinker

CAS : 68528-80-3

Ref. TM-T15176

Informations sur le produit

• Nom: DSS Crosslinker
• Synonymes: 2,5-Pyrrolidinedione, 1,1′-[(1,8-dioxo-1,8-octanediyl)bis(oxy)]bis-, Disuccinimidyl suberate, Disuccinimidylsuberate, NSC 340008, Octanedioic acid di-N-hydroxysuccinimide ester, Octanedioic acid, 1,8-bis(2,5-dioxo-1-pyrrolidinyl) ester, Suberic acid bis(N-hydroxy succinimide ester)
• CAS: 68528-80-3

Description

DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm that are used to conjugate proteins. DSS crosslinker can be used to conjugate or crosslink intracellular proteins.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 368.34
• Formule: C₁₆H₂₀N₂O₈
• Degré de pureté: 99.72%
• Couleur/Forme: Solid
• InChI: InChI=1S/C16H20N2O8/c19-11-7-8-12(20)17(11)25-15(23)5-3-1-2-4-6-16(24)26-18-13(21)9-10-14(18)22/h1-10H2
• Code InChI: InChIKey=ZWIBGKZDAWNIFC-UHFFFAOYSA-N
• SMILES: O=C(CCCCCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O