Pozanicline

CAS : 161417-03-4

Ref. TM-T16563

Informations sur le produit

• Nom: Pozanicline
• Synonymes: ABT-089, (S)-2-Methyl-3-(2-pyrrolidinylmethoxy)pyridine, 2-Methyl-3-(2S-pyrrolidinylmethoxy)pyridine, 2-Methyl-3-[(2S)-2-pyrrolidinylmethoxy]pyridine, 2-Methyl-3-[[(2S)-pyrrolidin-2-yl]methoxy]pyridine, A 87089.0, Abt 089, Pyridine, 2-methyl-3-((2S)-2-pyrrolidinylmethoxy)-, Pyridine, 2-methyl-3-(2-pyrrolidinylmethoxy)-, (S)-, Unii-Cl2002R563

Description

Pozanicline reverses nicotine withdrawal-induced cognitive deficits, may be an effective component of novel therapeutic strategies for nicotine addiction. Pozanicline selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a novel cholinergic agent that is a partial agonist at α4β2 nAChRs (Ki=16 nM). It shows high selectivity for α6β2 and α4α5β2 nAChR subtypes, the binding affinity (Ki, rat) for Pozanicline to [3H] cytisine sites is 16.7 nM .

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 192.26
• Formule: C₁₁H₁₆N₂O
• Degré de pureté: 98%
• Couleur/Forme: Solid