Bufalin

CAS : 465-21-4

Ref. TM-T1719

Informations sur le produit

• Nom: Bufalin
• Synonymes: (3Beta,5Beta,8Xi,9Xi)-3,14-Dihydroxybufa-20,22-Dienolide, (3β,5β)-3,14-Dihydroxybufa-20,22-dienolide, 3,14-Dihydroxybufa-20,22-Dienolide, 5β-Bufa-20,22-dienolide, 3β,14-dihydroxy-, B 0261, Bufa-20,22-dienolide, 3,14-dihydroxy-, (3β,5β)-, NSC 89595
• CAS: 465-21-4

Description

Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potential cardiotonic and antineoplastic activity. Although the mechanism of action of bufalin is still under investigation, this agent is a specific Na+/K+-ATPase inhibitor and can induce apoptosis in Y cell lines through the activation of the transcription factor AP-1 via a mitogen activated protein kinase (MAPK) pathway.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 386.52
• Formule: C₂₄H₃₄O₄
• Degré de pureté: 99.25%
• Couleur/Forme: White Solid