(Z)-Semaxinib

CAS : 194413-58-6

Ref. TM-T2496

Informations sur le produit

• Nom: (Z)-Semaxinib
• Synonymes: SU5416, (3Z)-3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one, (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one, (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one, (Z)-3-(3,5-Dimethylpyrrol-2-ylmethylene)indolin-2-one, (Z)-Su 5416, 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, (3Z)-, 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, (Z)-, 3-((2,4-Dimethylpyrrol-5-YL)METHYLIDENYL)-2-indolonone, 3-[1-(3,5-Dimethyl-1H-pyrrol-2-yl)meth-(Z)-ylidene]-2-oxo-2,3-dihydroindole, Nsc-696819, Semaxanib, Semoxind, Su-5416, Sugen, Tsu-16
• CAS: 194413-58-6

Description

(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition for FGFR, InsR, and EGFR. (Z)-Semaxinib is a quinolone derivative with potential antineoplastic activity.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 238.28
• Formule: C₁₅H₁₄N₂O
• Degré de pureté: 99.94%
• Couleur/Forme: Solid