(Rac)-SAR131675

CAS : 1092539-44-0

Ref. TM-T3691

Informations sur le produit

• Nom: (Rac)-SAR131675
• Synonymes: SAR131675
• CAS: 1092539-44-0

Description

(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is highly specific for VEGFR-3 versus 107 receptors, enzymes, ion channels, and 65 kinases. SAR131675 is a highly specific VEGFR-3-TK inhibitor with significant antitumoral and antimetastatic activities in vivo through inhibition of lymphangiogenesis and TAM invasion.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 358.39
• Formule: C₁₈H₂₂N₄O₄
• Degré de pureté: 99.1%
• Couleur/Forme: Solid