RORγt Inverse agonist 10

CAS : 2413986-35-1

Ref. TM-T40043

Informations sur le produit

• Nom: RORγt Inverse agonist 10
• Marque: Targetmol
• Description: RORγt Inverse agonist 10 is a highly potent, orally bioavailable compound that acts as an antagonist for the retinoic acid receptor-related orphan nuclear receptor gamma t (RORγt). With an IC50 of 51 nM, it effectively inhibits RORγt activity, a key transcription factor regulating genes linked to psoriasis pathogenesis, including [IL-17A], [IL-22], and [IL-23R].

Propriétés chimiques

• Masse moléculaire: 572.512
• Formule: C₂₅H₂₆F₆N₆O₃
• Couleur/Forme: Solid