ZNL 02-096

CAS : 2414418-49-6

Ref. TM-T41163

Informations sur le produit

• Nom: ZNL 02-096
• Synonymes: Pomalidomide-C3-adavosertib
• CAS: 2414418-49-6

Description

ZNL 02-096 (Pomalidomide-C3-adavosertib) is a rapid and selective degrader of Wee1 (IC50=3.58 nM).ZNL 02-096 selectively degrades Wee1 at submolar concentrations without damaging PLK1, a secondary target of AZD 1775.ZNL 02-096 induces degradation of Wee1 and accumulation of DNA damage in MOLT-4 cells in vitro, In vitro in MOLT-4 cells, ZNL 02-096 induced Wee1 degradation, accumulation of DNA damage, cell cycle arrest in G2/M phase and apoptosis.ZNL 02-096 showed anti-proliferative effects in 300 cancer cell lines.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 799.88
• Formule: C₄₂H₄₅N₁₁O₆
• Degré de pureté: 99.84%
• Couleur/Forme: Solid