Rauwolscine hydrochloride

CAS : 6211-32-1

Ref. TM-T4429

Informations sur le produit

• Nom: Rauwolscine hydrochloride
• Synonymes: Corynanthidine hydrochloride, α-Yohimbine hydrochloride, Isoyohimbine hydrochloride, (16Beta,17Alpha,20Alpha)-17-Hydroxy-16-(Methoxycarbonyl)Yohimban-4-Ium, 20α-Yohimban-16β-carboxylic acid, 17α-hydroxy-, methyl ester, monohydrochloride, Methyl (16Beta,17Alpha,20Alpha)-17-Hydroxyyohimban-16-Carboxylate, Methyl (16Beta,17Alpha,20Alpha)-17-Hydroxyyohimban-16-Carboxylate Hydrochloride (1:1), Methyl (16Beta,20Alpha)-17-Hydroxyyohimban-16-Carboxylate, Methyl (17Alpha,20Alpha)-17-Hydroxyyohimban-16-Carboxylate Hydrochloride, NSC 407307, Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, hydrochloride (1:1), (16β,17α,20α)-, Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, monohydrochloride, (16β,17α,20α)-, α-Yohimbine hydrochloride
• CAS: 6211-32-1

Description

Rauwolscine hydrochloride (Isoyohimbine hydrochloride) , a natural alkaloid, is a specific and reversible α2-adrenergic receptor antagonist (Ki: 12 nM) [1]. It is a stereoisomer of yohimbine, which potently antagonizes both α1- and α2-adrenergic receptors [1]. Rauwolscine hydrochloride also acts as a receptor antagonist at the serotonin 5-HT2B receptor (Ki: 14.3 nM) and as a weak partial agonist at 5-HT1A (IC50: 1.3 μM) [3]. The α2-adrenergic receptor has diverse physiological functions and antagonists like rauwolscine have numerous applications, including the modulation of mood and behavior [5].

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 390.9
• Formule: C₂₁H₂₇ClN₂O₃
• Degré de pureté: 100%
• Couleur/Forme: White Solid