Informations sur le produit
- DDD498, M 5717, MMV121
DDD107498 (DDD-498) is a potent and orally active antimalarial agent that inhibits multiple life-cycle stages of the parasite with an EC 50 of 1 nM against P. falciparum 3D7. DDD107498 inhibits protein synthesis by targeting eEF2/CaMKIII, with an EC 50 of 2 nM for WT- Pf eEF2 [1].