Tipifarnib

CAS : 192185-72-1

Ref. TM-T6271

Informations sur le produit

• Nom: Tipifarnib
• Synonymes: R115777, Zarnestra, IND 58359, (R)-(+)-R 115777, (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone, 2(1H)-Quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-, 6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one, Tipifarnib Zarnestra, Zarnestra
• CAS: 192185-72-1

Description

Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting the farnesylation of proteins, this agent prevents the activation of Ras oncogenes, inhibits cell growth, induces apoptosis, and inhibits angiogenesis.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 489.4
• Formule: C₂₇H₂₂Cl₂N₄O
• Degré de pureté: 99.22%
• Couleur/Forme: Off-White To Pale Beige Solid