PF-6689840

CAS : 1799790-53-6

Ref. TM-T67693

Informations sur le produit

• Nom: PF-6689840
• Marque: Targetmol
• Description: PF-6689840 is a potent and selective Type II PTK6/Brk inhibitor with IC50 of 54 nM in biochemical assays; inhibits PTK6 phosphorylation at Y342 in engineered HET293T cells overexpressing PTK6 WT with IC50 of 0.25 uM; demonstrates superior kinase selectivity compared to the Type I inhibitors; inhibits tumor cell growth, which is independent of PTK6 expression levels in cells.

Propriétés chimiques

• Masse moléculaire: 521.46
• Formule: C₂₄H₂₃F₄N₅O₄
• Couleur/Forme: Soild