N-5-Carboxypentyl-1-deoxynojirimycin

CAS : 79206-51-2

Ref. TM-T84411

Informations sur le produit

• Nom: N-5-Carboxypentyl-1-deoxynojirimycin
• Synonymes: N-5-Carboxypentyl-1-dNM, N-5-Carboxypentyl-1-DNJ, 1-Piperidinehexanoic acid, 3,4,5-trihydroxy-2-(hydroxymethyl)-, (2R,3R,4R,5S)-, (2R,3R,4R,5S)-3,4,5-Trihydroxy-2-(hydroxymethyl)-1-piperidinehexanoic acid, 1-Piperidinehexanoic acid, 3,4,5-trihydroxy-2-(hydroxymethyl)-, [2R-(2α,3β,4α,5β)]-

Description

1-Deoxynojirimycin, a potent glucose analog, inhibits α-glucosidase I and II effectively. Its derivative, N-5-Carboxypentyl-1-deoxynojirimycin, serves as a ligand for glucosidase I and II purification, utilizing carboxypentyl groups for affinity chromatography resin linkage. Furthermore, N-5-Carboxypentyl-1-deoxynojirimycin demonstrates comparable or superior inhibition of glucosidase compared to 1-deoxynojirimycin, with inhibition constants (Ki) of 0.45 µM and 2.1 µM, respectively, for pig liver glucosidase I.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 277.317
• Formule: C₁₂H₂₃NO₆
• Couleur/Forme: Liquid