N-Deacetylcolchicine

CAS : 3476-50-4

Ref. TM-T85194

Informations sur le produit

• Nom: N-Deacetylcolchicine
• Synonymes: NSC 201400, (-)-7-Deacetylcolchicine, (-)-Deacetylcolchicine, (7S)-7-Amino-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one, (7S)-7-Amino-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one, Benzo[a]heptalen-9(5H)-one, 7-amino-6,7-dihydro-1,2,3,10-tetramethoxy-, (S)-, Colchicine, N-deacetyl-, Colchicine, deacetyl-, Desacetylcolchicine, N-Desacetylcolchicine, benzo[a]heptalen-9(5H)-one, 7-amino-6,7-dihydro-1,2,3,10-tetramethoxy-, (7S)-

Description

Trimethylcolchicinic acid methyl ether (HAN 76504), an antimitotic agent, blocks microtubule assembly by attaching to tubulin and inhibiting its polymerization. It enhances tubulin's intrinsic GTPase activity, induces apoptosis across various normal and tumor cell lines, and activates the JNK/SAPK pathway. Currently unnamed, it is referred to by a provisional code name in line with MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming) for ease of communication.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 357.4
• Formule: C₂₀H₂₃NO₅
• Couleur/Forme: Solid