Balinatunfib

CAS : 2248726-53-4

Ref. TM-T89932

Informations sur le produit

• Nom: Balinatunfib
• Synonymes: TNFα activity modulator 3, SAR-441566, SAR441566, SAR 441566
• Marque: Targetmol
• Description: Balinatunfib (SAR-441566) is an orally active and highly selective inhibitor of TNFR1 signaling that exerts its mechanism of action by binding to the central pocket of the soluble TNFα (sTNFα) trimer, stabilizing an asymmetric and inactive conformation that selectively blocks interaction with TNFR1 without affecting TNFR2, Balinatunfib suppresses downstream proinflammatory signaling cascades and demonstrating robust anti-inflammatory activity suitable for mechanistic and translational research in autoimmune and inflammatory diseases.

Propriétés chimiques

• Masse moléculaire: 502.52
• Formule: C₂₇H₂₄F₂N₆O₂
• Degré de pureté: 99.20%
• Couleur/Forme: Orange Solid