NecroX-7

CAS : 1120332-55-9

Ref. TM-T9948

Informations sur le produit

• Nom: NecroX-7
• Synonymes: LC-280126, LC28-0126, LC28 0126
• CAS: 1120332-55-9

Description

NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. Additionally, NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 may be use for treatment of graft-versus-host disease (GVHD) research [1].

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 439.57
• Formule: C₂₄H₂₉N₃O₃S
• Degré de pureté: 98.08%
• Couleur/Forme: Solid