LRRC32 Protein, Human, Recombinant (hFc)

Ref. TM-TMPJ-00364

Informations sur le produit

• Nom: LRRC32 Protein, Human, Recombinant (hFc)
• Synonymes: D11S833E, GARPGarpin, GARP, Garpin

Description

Leucine Rich Repeat Containing 32 (LRRC32), also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naïve T cell proliferation. LRRC32 is widely expressed during embryogenesis and on adult platelets. Human LRRC32 is identified as a lineage specific key receptor for human T cells.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 110 KDa (reducing condition)
• Couleur/Forme: Solid