Cerberus 1/CER1 Protein, Human, Recombinant (HEK293, His)
Ref. TM-TMPJ-00716
1mg | 2.532,00 € | ||
10µg | 151,00 € | ||
50µg | 442,00 € | ||
500µg | 1.763,00 € |
Informations sur le produit
- DAN Domain Family Member 4, Cerberus, Cerberus-Related Protein, CER1, DAND4
Cerberus 1 is a secreted glycoprotein that forms disulfide-linked homodimers. It is a cytokine member of the DAN domain family of BMP antagonists that includes DAN (DAND1), Gremlin/Drm (DAND2), PRDC (Protein Related to Dan and Cerberus, DAND3), and COCO/Dante (DAND5). DAN family members contain a cysteine knot domain that is homologous to that found in other TGF-beta superfamily ligands. At the onset of gastrulation, Cerberus 1 is transiently expressed in anterior endodermal structures in response to Nodal and Shh. Cerberus 1 binds BMP-4 and Nodal and inhibits their activities. The inhibitory functions of Cerberus favor mesodermal development in the anterior region of the gastrula and suppresses posterior mesodermal differentiation. In chick and Xenopus, Cerberus 1 also regulates, but is not required for embryonic left-right polarization, neurulation, and head and heart induction.
Propriétés chimiques
Question d’ordre technique sur : TM-TMPJ-00716 Cerberus 1/CER1 Protein, Human, Recombinant (HEK293, His)
Si vous souhaitez demander un devis ou passer commande, veuillez plutôt ajouter les produits souhaités à votre panier, puis demander un devis ou passer commande à partir de votre panier. C'est une méthode plus rapide, plus économique, et vous pourrez bénéficier des remises disponibles ainsi que d'autres avantages