DNA PolymeraseBeta Protein, Human, Recombinant (His)

Ref. TM-TMPJ-00792

Informations sur le produit

• Nom: DNA PolymeraseBeta Protein, Human, Recombinant (His)
• Synonymes: DNA Polymeraseβ, POLB, DNA Polymerase Beta, DNA Polymerase β

Description

Human DNA polymerase β is constitutively expressed in cells. It fills in gaps in DNA that are formed following base excision repair. Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. It conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. The activity cannot be affected by Aphidicolin, which is an inhibitor of DNA polymerase β.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 39 KDa (reducing condition)
• Couleur/Forme: Solid