ITGA5 Protein, Human, Recombinant (His)

Ref. TM-TMPJ-00810

Informations sur le produit

• Nom: ITGA5 Protein, Human, Recombinant (His)
• Synonymes: FNRA, Integrin α-5, Integrin Alpha-F, Fibronectin Receptor Subunit α, Integrin Alpha-5, CD49 Antigen-Like Family Member E, VLA-5, Integrin α-F, CD49e, ITGA5, Fibronectin Receptor Subunit Alpha

Description

Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin α-5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains. In addition to adhesion, ITGA5 participates in cell-surface mediated signalling.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 130 KDa (reducing condition)
• Couleur/Forme: Solid