THOP1 Protein, Human, Recombinant (His)

Ref. TM-TMPJ-01008

Informations sur le produit

• Nom: THOP1 Protein, Human, Recombinant (His)
• Synonymes: THOP1, MP78, Thimet Oligopeptidase, Endopeptidase 24.15

Description

Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase. THOP1 is located in Cytoplasm. THOP1 is widely expressed in human tissues and can detected in different subcellular locations. THOP1 is preferential cleavage for bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues. THOP1 is involved in the metabolism of neuropeptides under 20 amino acid residues and degradation of cytoplasmic peptide. In addition, THOP1 also can degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 85 KDa (reducing condition)
• Couleur/Forme: Solid