TIM14 Protein, S. cerevisiae, Recombinant

Ref. TM-TMPJ-01087

Informations sur le produit

• Nom: TIM14 Protein, S. cerevisiae, Recombinant
• Synonymes: Mitochondrial import inner membrane translocase subunit TIM14, TIM14, Presequencetranslocated-associated motor subunit PAM18, PAM18

Description

Mitochondrial import inner membrane translocase subunit TIM14 (TIM14) is an essential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, TIM14 is required to stimulate activity of mtHSP70 (SSC1). TIM14 belongs to the DnaJ family, which has been involved in Hsp40/Hsp70 chaperone systems. As a mitochondrial chaperone, TIM14 functions as part of the TIM23 complex import motor to facilitate the import of nuclear-encoded proteins into the mitochondria. TIM14 also complexes with prohibitin complexes to regulate mitochondrial morphogenesis, and has been implicated in dilated cardiomyopathy with ataxia.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 9 KDa (reducing condition)
• Couleur/Forme: Solid