Sting Protein, Human, Recombinant (Sumo & His)

Ref. TM-TMPJ-01206

Informations sur le produit

• Nom: Sting Protein, Human, Recombinant (Sumo & His)
• Synonymes: TMEM173, Mediator of IRF3 activation, Stimulator of interferon genes protein, sting

Description

Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2, RNF5 and TRIM56 along with TBK1. This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 35 KDa (reducing condition)
• Couleur/Forme: Solid