SIRP alpha V2 Protein, Human, Recombinant (hFc)

Ref. TM-TMPK-00610

Informations sur le produit

• Nom: SIRP alpha V2 Protein, Human, Recombinant (hFc)
• Synonymes: PTPNS1, MYD-1, MFR, SHPS1, SIRPalpha2, SIRPα2, SIRPA, SIRP α V2/CD172a, BIT, MYD1, SHPS-1, CD172a, SIRP alpha, SIRP α, P84

Description

Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don't eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 63.9 kDa and the accession number is AAH26692.1.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 63.9 kDa (predicted). Due to glycosylation, the protein migrates to 75-85 kDa based on Tris-Bis PAGE result.
• Couleur/Forme: Solid