CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

Ref. TM-TMPK-00644

Informations sur le produit

• Nom: CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
• Synonymes: CD47, OA3, IAP, CD47 molecule, CD47 glycoprotein, MER6

Description

CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα).CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 15 kDa (predicted). Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.
• Couleur/Forme: Solid