CD37 Protein, Human, Recombinant (His)

Ref. TM-TMPK-00809

Informations sur le produit

• Nom: CD37 Protein, Human, Recombinant (His)
• Synonymes: Tspan-26, GP52-40, Tetraspanin-26, MGC120234, CD37 molecule, CD37

Description

CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and targeting this molecule may provide additional benefit to relapsed or refractory patients.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 15.72 kDa (predicted). Due to glycosylation, the protein migrates to 25-40 kDa based on Tris-Bis PAGE result.
• Couleur/Forme: Solid