HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi)

Ref. TM-TMPK-00836

Informations sur le produit

• Nom: HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi)
• Synonymes: MHC Class I Antigen G, HLA G antigen, HLA-G, sHLA-G, HLA G, b2 microglobulin, MHC class Ib antigen, MHC-G, HLAG

Description

HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 35.5 kDa (predicted). The protein migrates to 36-40 kDa based on Tris-Bis PAGE result.
• Couleur/Forme: Solid