KIR2DL3 Protein, Human, Recombinant (His & Avi)

Ref. TM-TMPK-00885

Informations sur le produit

• Nom: KIR2DL3 Protein, Human, Recombinant (His & Avi)
• Synonymes: KIR2DL3, NKAT-2, NKAT2A, KIR2DS5, KIRCL23, CD158B2, NKAT2B, KIR-K7b, NKAT, NKAT2, KIR-K7c, GL183, CD158b, cl-6

Description

KIR2DL3 (2DL3, formerly NKAT2, designated CD158b2) is a 341 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig-like receptor (KIR) family of molecules. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis. KIR2DL3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.3 kDa and the accession number is P43628.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 27.3 kDa (predicted). Due to glycosylation, the protein migrates to 45-52 kDa based on Tris-Bis PAGE result.
• Couleur/Forme: Solid