Siglec-8 Protein, Human, Recombinant (His & Avi)

Ref. TM-TMPK-01211

Informations sur le produit

• Nom: Siglec-8 Protein, Human, Recombinant (His & Avi)
• Synonymes: SIGLEC8, SAF2SAF-2, SAF2, CDw329, Siglec-8, MGC59785, SIGLEC8L

Description

Siglec-8, also known as SAF, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-8 consists of a 347 amino acid (aa) extracellular domain (ECD) with three Ig-like domains.Putative adhesion molecule that mediates sialic-acid dependent binding to red blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. Siglec-8 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 40.7 kDa and the accession number is Q9NYZ4.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 40.7 kDa (predicted). Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
• Couleur/Forme: Solid