Kremen-1 Protein, Human, Recombinant (His)

Ref. TM-TMPY-04144

Informations sur le produit

• Nom: Kremen-1 Protein, Human, Recombinant (His)
• Synonymes: KREMEN, KRM1, kringle containing transmembrane protein 1

Description

KREMEN1 (Kringle Containing Transmembrane Protein 1) is a Protein Coding gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The cell surface molecule KREMEN1 is an entry receptor for coxsackievirus A1 (CV-A10). Whereas loss of KREMEN1 renders cells resistant to CV-A10 infection, KREMEN1 overexpression enhances CV-A10 binding to the cell surface and increases susceptibility to infection, indicating that KREMEN1 is a rate-limiting factor for CV-A10 infection. KREMEN1 is also essential for infection by a phylogenetic and pathogenic related group of Human type A Enteroviruses (EV-As). Diseases associated with KREMEN1 include Ectodermal Dysplasia 13, Hair/Tooth Type, and Hand, Foot, And Mouth Disease.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 42.6 kDa (predicted)
• Couleur/Forme: Solid